Blood sugar health superfood capsules gynura procumbens. In vitro simulated digestion and in vivo metabolism of. Efficient in vitro micropropagation of gynura procumbens by. This study evaluated the in vivo hypoglycemic properties of the water extract of g. Assessment of analgesic and neuropharmacological activity of. It is usually used as a traditional medicine for the treatment of eruptive fevers, rash, kidney disease, migraines, constipation, hypertension, diabetes mellitus, and cancer.
Flowering heads are panicled, narrow, yellow, and 1 to 1. Malaysian journal of biochemistry and molecular biology 2008 162, 1014 10 effects of gynura procumbens extract and glibenclamide on sperm quality and specific activity of testicular lactate dehydrogenase in. Glucose absorption from the intestines and its glucose uptake in abdominal skeletal. Gynura procumbens improved fertility of diabetic rats. A total of 42 male rats were randomly sorted into six groups. Gynura procumbens sabungai is a twining vine, smooth except for the peduncles. It works against virus, inflammation and various types of allergies. The purpose of the present study was to qualitatively evaluate antimicrobial effects of gynura procumbens extracts. Research article antiherpetic effects of gynura procumbens siripenjarikasem, 1,2 somyotcharuwichitratana, 3 sontanasiritantikorn, 4 wasanchantratita, 5 magdyiskander, 6 augustwilhelmfrahm, 7 andweenajiratchariyakul 1 department of pharmacognosy, faculty of pharmacy, mahidol university, sri ayudhya road, rajathevi district, bangkok, a iland. Extracts on antiproliferative activity and its associated morphological changes of human. Throughout the years, intensive research done on g. Being an anti viral and antiinflammatory herb it has the ability to help regulate not only the blood glucose, but also blood. Containing abundant proteins, it also exhibited free radical scavenging and iron chelating properties thus pointing to its high nutritional value and antioxidant effect.
It was further chromatographed on mci gel chp20p column giving the extract fractions f1 water, f2 watermethanol f3 methanol, and f4 ethyl acetate. However, there is little toxicological information available regarding safety following repeated exposure. Antidiabetic properties and mechanism of action of gynura. Gynura procumbens gp commonly known as longevity spinach is one of those precious. This is a very low maintenance, fast growing herbvegetable that can be grown indoor and outdoor. For subchronic toxicity studies, the rats were orally administered the methanol extract of gynura procumbens at the doses of 125, 250, and 500 mgkg day for a period of weeks. Antihypertensive effects of gynura procumbens extract in. With divine providence, gynura procumbens put the last touch that completely brought my husband back to normalcy. A new cerebroside from the roots of gynura procumbens. Gynura procumbens is an alkalizing vegetable that is rich in vitamins and antioxidants that are beneficial for anyone with high blood glucose diabetes, high cholesterol, hypertension, rheumatism, viral problems, and other ailments. Gynura procumbens, a local herb with antihyperglycemic and antidiabetic properties, has been traditionally used to. Gynura procumbens is a medicinally important herbaceous plant species belonging to the family asteraceae. Leaves are stalked the uppermost ones stalkless, ovateelliptic or lanceolate, 3. Anticarcinogenesis effect of gynura procumbens lour merr on.
This study was carried out to investigate the antiinflammatory therapeutic effects of gynura procumbens ethanolic. Diabetes living providing natural solutions for improved. Merr family compositae is cultivated in southeast asia, especially indonesia, malaysia and thailand, for medicinal purposes. Gynura procumbens is a medicinal plant traditionally used in treating various ailments including inflammation but the mechanism of antiinflammatory activity of this plant is still elusive. Gynura procumbens, medicinal plant, biological activity. Jun 17, 2019 chemical constituents of the stems of gynura procumbens. Evaluation of antioxidant properties, cytotoxicity and acute.
Traditionally, it is widely used in many different countries for the treatment of a wide variety of health ailments such as kidney discomfort, rheumatism, diabetes mellitus, constipation, and hypertension. Gynura procumbens can be eaten fresh like a salad, stir fried with other vegetables, juiced, and also enjoyed as a cup of tea. Compositae, commonly called sambung nyawa in malaysia, are often eaten raw with rice. Agronomic practices and future prospects in malaysia. Antioxidant potential of gynura procumbens rosidah, mun fei yam, amirin sadikun, and mohd. Zaini asmawi school of pharmaceutical sciences, universiti sains malaysia, pulau pinang, malaysia abstract the leaves of gynura procumbens merr.
Gynura procumbens, medicinal plant, biological activity, g. Various studies on methanol extracts of the leaves of gynura procumbens demonstrated its antihyperglycemic, antihyperlipidemic, antiinflammatory, antiulceronegenic properties. International journal of pharmtech research coden usa. Please click here to see the true ashitaba tomorrow leaf. An overview of the gynura procumbens leaves extraction and. The purpose of this plant is to incorporate it into your diet for. It was further chromatographed on mci gel chp20p column giving the extract fractions f1 water, f2 watermethanol f3.
Gynura procumbens ethanolic extract suppresses osteosarcoma. Information about the openaccess article anticarcinogenesis effect of gynura procumbens lour merr on tongue carcinogenesis in 4nqoinduced rat in doaj. Longevity plant for diabetes and highcholesterol gynura. To study the antidiabetic activity of gynura procumbens g. Gynura procumbens is very closely related to gynura bicolor aka okinawan spinach, and sometimes mistaken with. Jan 04, 2007 aqueous extracts of gynura procumbens lour. Cultivation and harvesting sabungai is a perennial, climbing vine, growing wild on edges of tropical forests and bushes, meadows, near streams, or other wet but well drained soils, and semishady places. This study was carried out to determine the effects of gp on blood glucose level, fertility and libido of streptozotocininduced male rats. Research articleeffects of extracts and fractions of gynura procumbens on rat atrial contraction omar saad saleh abrika1, mun fei yam1, mohd. This work was kindly supported by the foundation of key project of research and development program of jiangxi province nos. Gynura procumbens is a wellknown traditional herb in south east asia. This study was designed to prepare caffeoylquinic acids rich and poor fractions of the ethanolic extract using resin column technology and compare their antihyperlipidemic and antioxidant potentials.
The antimicrobial properties of gynura procumbens sambung. Effect of gynura procumbens extracts on antiproliferative. New zealand white rabbits were fed with high cholesterol diet for ten weeks. The extracts were further subjected to phytochemical. Gynura procumbens, medicinal plant, phytochemical, pharmacological. Gynura procumbens, diabetes mellitus type 1, sperm quality, testosterone introduction. Gynura procumbens leaf improves blood glucose level. All but f1 had virucidal action against both viral types.
The antioxidant activity and metabolites of chlorogenic acid dimer from gynura procumbens lour. Let us share a story with you about someone who is very special to diabetes living. Researcharticle gynura procumbens improved fertility of diabetic rats. Nov 11, 2019 this work was kindly supported by the foundation of key project of research and development program of jiangxi province nos. Our earlier study showed the presence of valuable plant defense proteins, such as peroxidase, thaumatinlike proteins and. Malaysian journal of biochemistry and molecular biology 2008 162, 1014 10 effects of gynura procumbens extract and glibenclamide on sperm. Merr is a wellknown traditional herb and is widely used for traditional medicine by. March 2019 daru journal of pharmaceutical sciences. Diabetes living providing natural solutions for improved health. Sep 10, 2014 efficient in vitro micropropagation of gynura procumbens published on sep 10, 2014 gynura procumbens is a medicinally important herbaceous plant species belonging to the family asteraceae. Longevity spinach is related to but not the same as okinawa spinach, with the scientific name of gynura procumbens, from the family asteraceae.
Mar 19, 20 to study the antidiabetic activity of gynura procumbens g. Gynura procumbens is a traditional herb used for the treatment of inflammation, rheumatism and viral infections, although the antitumor effect and its potential mechanisms of action remain unclear. Gynura procumbens belongs to family asteraceae is a fast. Pdf antiherpetic effects of gynura procumbens somyot. Antioxidant potential in different parts and callus of. An overview of the gynura procumbens leaves extraction and potential of hybrid predictive tools application for prediction and simulation in supercritical fluid extraction. Sabungai, gynura procumbens, longevity spinach, bai bing ca philippine herbal medicine an illustrated compilation of philippine medicinal plants by dr godofredo umali stuart, with botanical information, chemical properties, folkloric uses and medicinal research studies. Several nonenzymatic antioxidants methods were utilized to study the antioxidant. In this study, the effects of gp aqueous extract gpae on diabetic rats were investigated through evaluating testes. Nonetheless, gynura procumbens extract also showed potential in the medical usage as a topical antiinflammatory agent iskander et al.
It is used to treat rheumatic fever, migraine, kidney disease, diabetes. Gynura procumbens which is locally known as sambung nyawa in malay. Gynura herb fights herpes simplex infections journal of. Gynura procumbens is one of the important medicinal plants in thailand and southeast asia. Lets take a look at the science and some of the active compounds for this antiviral herb. Toxicology evaluation of standardized methanol extract of.
Merrill gynura procumbens is extremely effective on type 2 diabetes and has proven to lower blood glucose on type 1 diabetes as well. Caffeoylquinic acids rich versus poor fractions of gynura. Researcharticle gynura procumbens improved fertility of. For acute toxicity studies, a methanol extract of gynura procumbens was orally administered to spraguedawley rats female and male at a dose range of 5000 mgkg. Abstract a revision of the paleotropical genus gynura cass. Pdf gynura procumbens gp commonly known as longevity spinach is one of those precious. Chemical constituents of the stems of gynura procumbens. The ethanol extract ofgynura procumbensshowed virucidal and antireplicative actions against herpes simplex virus hsv1 and hsv2.
The medicinal plant gynura procumbens cures diabetes. This plant is about 1025 cm high and it is presented with succulent, elliptic and glossy purplish leaves. Gynura procumbens is well known for its various medicinal properties such as antihyperglycaemic, antihyperlipidaemic, and antiulcerogenic. The present study determined nutritional value in various parameters such as moisture content, carbohydrate, protein, lipid as standard methods and evaluated the antioxidative properties of the medicinal plant gynura procumbens extract by hydroxyl scavenging activity, ferrous ionchelating activity and inhibition of lipid peroxidation. Family asteraceae is a medicinal plant commonly found in tropical asia countries such as china, thailand, indonesia, malaysia, and vietnam. In vitro propagation and ex vitro establishment of a medicinal plant gynura procumbens lour. As vegetarians, we were delighted to discover that longevity spinach is high in quality. Jul 12, 2018 gynura procumbens gp is a medicinal herb that has long been known as antiinflammatory and antihyperglycaemic. Gynura procumbens is not toxic and exhibit antidiabetic, antiinflammatory, antihypertensive and wound healing properties where the extract of this plant contains active chemical constituents such as tannins, terpenoids, sterol glycoside, saponins and flavonoids. The methanol extract was prepared from the dried leaves using a soxhlet apparatus. Zaini asmawi1, amirin sadikun1, hamady dieng2, elssanousi ali hussain1 1school of pharmaceutical sciences, universiti sains malaysia, penang, malaysia 2school of biological sciences, universiti sains malaysia, penang. The anticancer property of proteins extracted from gynura.
Growing longevity spinach gynura procumbens medicinal. Although the potential of gynura procumbens extract in antiinflammatory effect has been shown in vitro and in vivo, a more comprehensive investigation on antiinflammatory mechanism by gynura procumbens. In vitro regeneration and ex vitro establishment of an. In vitro regeneration and ex vitro establishment of an antidiabetic plant gynura procumbens lour. Preliminary study of sperm proteomic khaidatulakmarkamaruzaman,1 wanmohdaizat,2. Gynura procumbens, phytoconstituents, pharmacological properties, toxicity. The ethanol extract of gynura procumbens showed virucidal and antireplicative actions against herpes simplex virus hsv1 and hsv2.
Plants from gynura family was used in this study, namely, gynura procumbens and gynura bicolor. Evaluation of phytochemical composition and antibacterial. The plant is a wellknown traditional herb in south east asia and it is widely used to treat inflammation, kidney discomfort, high cholesterol level, diabetic, cancer and high blood pressure. Efficient in vitro micropropagation of gynura procumbens an important rare medicinal plant, through shoot tip and nodal segment explants journal of research in biology 2014 46. Research article antiherpetic effects of gynura procumbens. Inhibitory effects of gynura procumbens ethanolic extract. Gynura procumbens belonging to asteraceae family is a medicinal plant commonly found in tropical asian countries such as bangladesh, india, china, thailand, indonesia, malaysia, and vietnam. Recently, this herbal extract has been associated with a profertility effect, suggesting its applicability in treating both diabetes and male infertility.
Oct 05, 2011 please do not get the wrong impression that gynura procumbens has done it all. Traditionally, it is widely used in many different countries for the treatment of a wide variety of health ailments such as kidney discomfort, rheumatism, diabetes mellitus. Hypoglycemic and antihyperglycemic study of gynura. Glucose absorption from the intestines and its glucose uptake in. Antioxidant potential in different parts and callus of gynura. Chemical constituents and bioactivity of gynura procumbens. The gynura herb gynura procumbens is a potent antiviral against herpes simplex virus 1 and hsv2 according to human and laboratory research. Sabungai, gynura procumbens, longevity spinach, bai bing ca. Inhibitory effects of gynura procumbens ethanolic extract on. Traditionally, it is widely used in many different countries for the treatment. Asteraceae is mainly popular in southeast asian countries for its traditional medicinal properties. Gynura procumbens gp has been widely used in traditional medicine due to its ability in treating various types of diseases.
In the present study, the antitumor effect of gynura procumbens ethanolic extract gpe on the osteosarcoma os cell line, u2. Procumbens is a lowgrowing, semisucculent leaf vegetable very popular in southeast asia, its home turf. It is usually used as a traditional medicine for the treatment of inflammation, herpes simplex virus, rashes, fever, rheumatism, kidney disease, migraines, constipation, diabetes mellitus, cancer and hypertension. Effects of extracts and fractions of gynura procumbens on. Assessment of analgesic and neuropharmacological activity. International journal of advanced research in botany ijarb page 9 explant, suggested by rajeswari and paliwal 2008 in pterocarpussantalinus. The medicinal plant gynura procumbens cures diabetes mellitus. International journal of advanced research in botany ijarb page 8 respectively on the same media formulation fig. Gynura procumbens also known as sabungai or sambung nyawa, sometimes called longevity spinach or longevity greens, is an edible vine found in china, southeast asia, and africa. Effects of gynura procumbens extract and glibenclamide on. He still does his daily walk and takes his maintenance drugs pioglitazone, metformin, acarbose, diamicron, norvasc, omacor and coralan.
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